WebAllogeneic hematopoietic cell transplantation (allo-HCT) is a potentially curative treatment for acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL). While many factors influence the outcomes of allo-HCT, the independent impact of donor-recipient ABO mismatching remains unclear. WebAug 1, 2013 · Patients with major ABO incompatibility receive platelet and plasma transfusions of donor type and RBC transfusions of recipient type during the first period after the transplantation and switch over to donor blood type when conversion of the ABO blood group is observed and antidonor alloantibody titers are undetectable.
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WebAllogeneic hematopoietic cell transplantation (allo-HCT) is a potentially curative treatment for acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL). While many … WebWe analyzed 512 patients after allogeneic peripheral blood SCT (allo-PBSCT) for an association of ABO mismatch with transfusion requirements, myeloid and platelet engraftment, the incidence of GvHD, relapse, transplant-related mortality (TRM), and … richard steyn
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WebDec 2, 2016 · ABO incompatibility between mother and fetus plays a protective role against RBC alloimmunization, presumably because of maternal isohemagglutinins rapidly clearing fetal RBCs from the maternal circulation. In addition to fetal/maternal bleeds, ... WebAllogeneic hematopoietic stem-cell transplantation (HSCT) remains the key curative treatment modality for various hematologic malignancies, bone marrow failure syndromes, and some hemoglobinopathies. An HLA-matched donor has traditionally been the donor of choice in HSCT due to superior outcomes associated with HLA-matching. WebDec 4, 2024 · This articles describes considerations for platelet ABO and RhD selection for platelet transfusions, including the impact of major ABO incompatibility on count increments, the risks of hemolysis associated with minor ABO incompatibility, and the risk of RhD alloimmunization when RhD-negative patients receive platelets obtained from RhD … richards texas