WebFigure 5. Gibbs free energy of solvation (ΔGsolv) calculated using Equation (1) for singly and doubly substituted Cy5 dyes in (a) water and (b) pyridine, quinoline, and isoquinoline. Singly and ... WebAlexa Fluor 680 Dye: An Alternative to the Cy5.5 Dye. With a peak excitation at 679 nm and maximum emission at 702 nm, Alexa Fluor 680 dye is spectrally similar to Cy5.5 dye (Figure 1.26). Fluorescence emission of Alexa Fluor 680 dye is well separated from that of other commonly used red fluorophores, such as the tetramethylrhodamine, Texas Red ...

Facile synthesis of thiol-reactive Cy3 and Cy5 derivatives …

WebOct 9, 2024 · We demonstrate the use of common cyanine dyes Cy3 and Cy5 as vectors for targeting and delivering cargoes to mitochondria in cancer cells. Specifically, conjugation to the dyes can increase cytotoxicity by up to 1000-fold. ... that impairs mitochondrial function and leads to apoptosis. 39 The synthesis of all drug conjugates proved to be rapid ... WebBio-Synthesis offers Cy5 fluorescent dye oligonucleotide labeling. Cy5 dye is compatible with various instrumentation including many fluorescent microscopes, imagers, scanners, … snowman office chair cover

Cy5 dye Thermo Fisher Scientific - AU

WebFeb 1, 2010 · A water-soluble pentamethine cyanine dye was synthesized for further conjugation with peptides. The dye preparation was accomplished by solution-phase … WebInvitrogen Cy5 dye is a bright, far-red-fluorescent dye with excitation ideally suited for the 633 nm or 647 nm laser lines. A significant advantage to using long wavelength dyes such as Cy5 dye or Invitrogen Alexa Fluor 647 dye over other fluorophores is the low autofluorescence of biological specimens in this region of the spectrum. WebFor the synthesis of the methyl Cy5 dye and its NHS ester (see Fig. 3 ), the three-carbon spacer (15) had to be prepared. Conden- sation of commercially available malondialdehyde bis (dimethyl ... snowman on a bike