The function of Thy-1 has not yet been fully elucidated. It has speculated roles in cell-cell and cell-matrix interactions, with implication in neurite outgrowth, nerve regeneration, apoptosis, metastasis, inflammation, and fibrosis. The Thy-1 knockout (KO) mice are viable and appear grossly normal. They display normal social interactions and normal learning in a maze, but fail to learn from social cues (e.g. learning from … Nettet18. nov. 2010 · InTeGrin Alpha X (ITGAX), the alpha subunit of (iC3b) receptor 4 (CR4). It is a type I transmembrane protein found on monocytes, macrophages, neutrophils, and some B cells that induces cellular activation and helps trigger neutrophil respiratory burst; expressed in hairy cell leukemias, acute nonlymphocytic leukemias, and some B-cell …
Frontiers Thy-1 in Integrin Mediated Mechanotransduction
NettetThy-1 is an abundant neuronal glycoprotein of poorly defined function. We recently provided evidence indicating that Thy-1 clusters a beta3-containing integrin in … NettetPancreatic Ductal Adenocarcinoma (PDAC) is a fatal disease with poor prognosis because patients rarely express symptoms in initial stages, which prevents early detection and diagnosis. Syndecans, a subfamily of proteoglycans, are involved in many physiological processes including cell proliferation, adhesion, and migration. Syndecans are … jeb\u0027s auto repair kawaihae telephone number
The multiple roles of Thy-1 in cell differentiation and regeneration
NettetCollectively, existing evidence suggests Thy-1 as a dual-functional integrin regulator —mediating integrin downstream signaling through direct trans -interaction, while also … Nettet25. feb. 2024 · Thy-1 in Integrin Mediated Mechanotransduction The glycosylphosphatidylinositol (GPI) anchored glycoprotein Thy-1 has been prevalently … Nettet21. mar. 2024 · THY1 (Thy-1 Cell Surface Antigen) is a Protein Coding gene. Diseases associated with THY1 include Retinal Artery Occlusion and Thymoma . Among its related pathways are Metabolism of proteins and Integrin Pathway . Gene Ontology (GO) annotations related to this gene include protein kinase binding and GTPase activator … ladybird beetle meaning bengali