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Web26 jun. 2007 · The integrin (ITG) molecule is composed of a transmembrane-type heterodimer that consists of an a chain and a b chain. ... 11 ITG family genes (ITGA1 … WebWe present a novel finding that the ITG family has a role in pathogenesis and CNS dysfunction in HD. Since ITGs are therapeutically targetable (26, 27) and manipulation of ITG-mediated signaling through ECM modulation prevents neurodegeneration and stimulates autophagy in other disease models ... philadelphia flyers echl affiliate
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