Thymocyte selection-associated hmg box
WebbThe immunogen of 21162-1-AP is TOX2 Fusion Protein expressed in E. coli. Background Information TOX2 is a transcription factor belonging to the TOX (thymocyte selection-associated HMG box) family that shares a highly conserved high mobility group DNA-binding domain with the other TOX members. Webb24 sep. 2024 · Thymocyte selection-associated high mobility group box protein (TOX) is a 526 aa nuclear protein (molecular weight, 57 kD) that binds DNA in a structure …
Thymocyte selection-associated hmg box
Did you know?
Webb19 feb. 2002 · The Journal of experimental medicine. 2004. TLDR. It is demonstrated that expression of the HMG box protein TOX is sufficient to induce changes in coreceptor … Webb开馆时间：周一至周日7:00-22:30 周五 7:00-12:00; 我的图书馆
Webb9 aug. 2024 · The tumor immune microenvironment (TIME) has been extensively recognized to be a crucial regulator of cancer progression, clinical outcome and therapeutic response., Tumor-infiltrating CD8+T cells form a significant component of the TIME and serve a key role in recognizing and killing tumor cells. Webb8 juli 2024 · Interestingly, increased PD-1, LAG3, TIM3, and thymocyte selection-associated HMG box (TOX) expression were observed with loss of PD-L1 on dendritic cells, …
Webb11 dec. 2024 · Among them, thymocyte selection–associated HMG-box protein (TOX) was identified as a central transcription regulator in T FH cell development. TOX is highly up-regulated in both mouse and human T FH cells in a BCL6-dependent manner. WebbClone REA473 recognizes the human and mouse TOX antigen, a member of an evolutionarily conserved DNA-binding protein family, and also known as thymocyte …
WebbCD8 + T cell exhaustion is a hallmark of many cancers and chronic infections. In mice, T cell factor 1 (TCF-1) maintains exhausted CD8 + T cell responses, whereas thymocyte …
Webb17 juni 2024 · In particular, the transcription factor thymocyte selection-associated HMG box protein (TOX) and several of its targets, including immune checkpoints, were over … biscotto schoko butterkeks motiveWebbChromatin accessibility analysis of HCV specific CD8 + T-cell responses reveals epigenetic signatures of exhaustion that appear to be reversible only to a limited extent after HCV elimination, for example, an epigenetic scar remains in super-enhancers near the TOX (thymocyte selection-associated HMG BOX) and HIF1α (hypoxia inducible factor-1α) … dark brown to luggage burgundy blondeWebbThe SRY-related HMG-box 17 (Sox17) is one of the first transcription factors exclusively expressed in the endoderm during early development, and its identification was a key … dark brown to medium golden brownWebbTOX (thymocyte selection-associated high mobility group (HMG) box protein) is a member of the HMG box family of DNA-binding proteins and likely plays a role in the regulation … biscouette creationWebb7 maj 2009 · Here, we determined the gene expression signature of peripheral CD8 + T cells undergoing deletional tolerance, relative to those undergoing immunogenic priming or lymphopenia-induced proliferation. From these data, we report the first detailed molecular signature of cells undergoing deletion. biscotto thunWebbAbstract TOX (thymocyte selection-associated HMG BOX) is a member of a family of transcriptional factors that contain the highly conserved high mobility group box (HMG … dark brown to light brown hair at homeWebb20 mars 2024 · TOX (thymocyte selection-associated HMG BOX) is a member of a family of transcriptional factors that contain the highly conserved high mobility group box (HMG-box) region. Increasing... dark brown toothbrush holder